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ALTEX: Current Issue 2014: Vol 31, No. 4


(All Articles are in PDF)

Sonja von Aulock


Grace Patlewicz, Nicholas Ball, Richard A. Becker, Ewan D. Booth, Mark T. D. Cronin, Dinant Kroese, David Steup, Ben van Ravenzwaay and Thomas Hartung
Read-across approaches – misconceptions, promises and challenges ahead


Marilena P. Etna, Elena Giacomini, Martina Severa, Manuela Pardini, Nacho Aguilo, Carlos Martin and Eliana M. Coccia
A human dendritic cell-based in vitro model to assess Mycobacterium tuberculosis SO2 vaccine immunogenicity

Catherine Willett, Jessica Caverly Rae, Katy O. Goyak, Brigitte Landesmann, Gary Minsavage and Carl Westmoreland
Pathway-based toxicity: History, current approaches, and liver fibrosis and steatosis as prototypes

Domenico Gadaleta, Fabiola Pizzo, Anna Lombardo, Angelo Carotti, Sylvia E. Escher, Orazio Nicolotti and Emilio Benfenati
A k-NN algorithm for predicting oral sub-chronic toxicity in the rat
Part 1
Part 2

Veit-Simon Eckle, Berthold Drexler, Christian Grasshoff, Thomas Seeger, Horst Thiermann and Bernd Antkowiak
Spinal cord – skeletal muscle cocultures detect muscle-relaxant action of botulinum neurotoxin A

t4 Report

Natalie Alépée, Anthony Bahinski, Mardas Daneshian, Bart De Wever, Ellen Fritsche, Alan Goldberg, Jan Hansmann, Thomas Hartung, John Haycock, Helena T. Hogberg, Lisa Hoelting, Jens M. Kelm, Suzanne Kadereit, Emily McVey, Robert Landsiedel, Marcel Leist, Marc Lübberstedt, Fozia Noor, Christian Pellevoisin, Dirk Petersohn, Uwe Pfannenbecker, Kerstin Reisinger, Tzutzuy Ramirez, Barbara Rothen-Rutishauser, Monika Schäfer-Korting, Katrin Zeilinger and Marie-Gabriele Zurich
State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology

Erwin van Vliet, Mardas Daneshian, Mario Beilmann, Anthony Davies, Eugenio Fava, Roland Fleck, Yvon Julé, Manfred Kansy, Stefan Kustermann, Peter Macko, William R. Mundy, Adrian Roth, Christoph Sachse, Imran Shah, Marianne Uteng, Bob van de Water, Thomas Hartung and Marcel Leist
Current approaches and future role of high content imaging in safety sciences and drug discovery


Piero Amodio, Paul Andrews, Marinella Salemme, Giovanna Ponte and Graziano Fiorito
The use of artificial crabs for testing predatory behavior and health in the octopus
Part 1
Part 2


Catherine Willett, Jessica Caverly Rae, Katy O. Goyak, Gary Minsavage, Carl Westmoreland, Melvin Andersen, Mark Avigan, Daniel Duché, Georgina Harris, Thomas Hartung, Hartmut Jaeschke, Andre Kleensang, Brigitte Landesmann, Suzanne Martos, Marilyn Matevia, Colleen Toole, Andrew Rowan, Terry Schultz, Jennifer Seed, John Senior, Imran Shah, Kas Subramanian, Mathieu Vinken and Paul Watkins
Building shared experience to advance practical application of pathway-based toxicology: Liver toxicity mode-of-action

Saskia M. Burm, Jan-Bas Prins, Jan Langermans and Jeffrey J. Bajramovic
Alternative methods for the use of non-human primates in biomedical researchMeeting Report

Meeting Report

Stefanie Schindler and Sonja von Aulock
The 9th World Congress on Alternatives and Animal Use in the Life Science

New ALTEX: 2/2018

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Online Humane Science Course


Building a Better Epithelium: Breaking the Barrier to the Next Generation of Toxicity Testing
March 10, 2018
San Antonio, TX

SOT Satellite Meeting: Updates on Activities Related to 21st Century Toxicology and Related Efforts: Invited Presentations and Open Mic
March 15, 2018
San Antonio, TX

Social Housing Workshop
June 4-5, 2018
Beltsville, MD

2nd Pan-American Conference for Alternative Methods
August 23-24, 2018
Rio de Janeiro, Brazil 

Eurotox 2018
September 2-5, 2018
Brussels, Belgium

20th International Congress on In Vitro Toxicology (ESTIV2018)
October 15-18, 2018

More Meetings...