Alternative Methods to the Mouse LD50 Assay for Botulinum Toxin Potency Testing

A request for comments, nominations of experts, and submission of in vivo and in vitro data for a proposed workshop on alternative methods to replace the Mouse LD50 Assay for Botulinum Toxin Potency Testing was announced in the Federal Register (Vol. 71, No. 18, pp. 4603-4) on January 27, 2006. Copies of the notice can be found at: http://iccvam.niehs.nih.gov/docs/FR/7104603.pdf in PDF or http://iccvam.niehs.nih.gov/docs/FR/7104603.htm in HTML.

This notice is in response to a nomination made to NICEATM by the Humane Society of the United States (HSUS) in October 2005. The HSUS nomination is available on the "Nominations and Submissions" page at http://iccvam.niehs.nih.gov/nomsub/submission.htm.

Please send public comment, nominations and data submissions by COB, March 13, 2006, to:
e-mail: niceatm@niehs.nih.gov
fax: 919-541-0947, or
mail:
Dr. William S. Stokes, Director
NICEATM, NIEHS
79 T.W. Alexander Drive
PO Box 12233
MD EC-17
Research Triangle Park, NC 27709

This notice can also be accessed through the ICCVAM home page at http://iccvam.niehs.nih.gov/ using the links in the "Announcements" box.