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CAAT-Europe Information Day: October 28th, 2010, Konstanz, Germany

REACH, TSCA Reauthorization and Toxicology of 21st Century

The Center for Alternatives to Animal Testing in Europe (CAAT-EU) operates as a joint venture of the University of Konstanz, Germany and CAAT at Johns Hopkins University, Baltimore, to provide first-hand, state-of-the-art information about alternative methods and their use in meeting regulatory requirements.

CAAT-EU invites you to the first in a series of high level Information Days. The October 28 event will focus on the status quo of REACH, the US Toxic Substance Control Act (TSCA) reauthorization, and the implementation of the US National Research Council strategy for Toxicity Testing in the 21st Century.

The REACH directive in the EU and the emerging TSCA reauthorization in the US are largescale programs to obtain toxicological data for old compounds, which prompt testing needs and changes in methods. This Information day aims to give a status update on REACH and TSCA to a European audience. Moreover, CAAT-EU will introduce the report of US National Research Council, Toxicity Testing in the 21st Century which put forward the vision on advanced toxicity testing and human health assessment. The authors describe in this report that the explanatory power of toxicological risk assessment can be maximized by employing high throughput in vitro screening assays, tests in lower organisms, systems biology, functional genomics and transcriptomics as well as predictive in silico approaches. This Information day aims to introduce this vision to a European audience by inviting some of the key US players as speakers.

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