Practical Training Course on Integrated Fludic Models for In-Vitro Testing

17-18 September 2012

Organized by: ISTITUTO SUPERIORE DI SANITÀ
Environmental and Primary Prevention Department and
INTERDEPARTMENTAL RESEARCH CENTER "E. PIAGGIO" UNIVERSITY OF PISA

N° ID: 092C12

The establishment of new in-vitro models requires an evolution of technology in order to allow researchers to implement new and physiologically relevant situations. The word “relevant” refers to the correspondence between in-vitro models and human physiology To this end, a modular fluidics system was developed in InLiveTox to model the response of cells and tissues to ingested nanomaterials. The system is more convenient and ethically less questionable than animal testing as well as more relevant than the in-vitro single cell culture /co-culture models currently being used.
This course has the goal of presenting the InLiveTox concept and fluidic systems to researchers involved in toxicity testing, barrier models and with a strong interest in refining in-vitro test systems as a means of reducing animal tests. These attractive and low cost devices will allow researchers to surpass the problems related to simulation of a physiological tissue in-vitro, in order to obtain a relevant model of an organ or multi organ system.

Language: the official language of the Course will be English

SCIENTIFIC PROGRAM

Monday, September 17
12.00 Participants Registration and snacks
14.30 Introductory Remarks - Arti Ahluwalia
14.50 Alternative testing and CELLTOX mission - Isabella De Angelis
15.10 Overview of research on in-vitro alternatives to animal testing -
Candida Nastrucci
15.30 The business of alternatives - Malcolm Wilkinson
15.50 Overview of nanotoxicology - Flavia Barone
16.10 Theoretical description of fluidics and scaling - Arti Ahluwalia
16.30 InLiveTox system (ILT0 and ILT2) - Sher Ahmed
16.50 Logistics for laboratory - Tommaso Sbrana
17.10 General discussion
17.30 End of the day
19.30 Conference dinner (optional, not included in the registration fee)

Tuesday, September 18
8.30 Nanoparticle handling (Lab - Module I ) - Arti Ahluwalia
10.30 Coffee break
11.00 Microfluidcs set up (Lab-Module II) - Sher Ahmed and Tommaso Sbrana
12.30 Lunch
14.00 Cell assays (Lab - Module III) - Sher Ahmed and Tommaso Sbrana
15.30 Coffee Break
16.00 TEER measurements (Lab - Module IV) Sher Ahmed and Tommaso Sbrana
17.30 General discussion and participants evaluation test

TUTORS
ARTI AHLUWALIA - Interdepartmental Research Center "E. Piaggio" University of Pisa, Pisa , Italy
SHER AHMED - CSEM, Neuchatel, CH, Switzerland Flavia Barone - Environmental and Primary Prevention Dpt., ISS, Rome, Italy
ISABELLA De ANGELIS - Environmental and Primary Prevention Dpt., ISS, Rome, Italy
CANDIDA NASTRUCCI - University of Rome “Tor Vergata”, Rome, Italy
TOMMASO SBRANA - Interdepartmental Research Center "E. Piaggio" University of Pisa, Pisa , Italy
MALCOM WILKINSON - Kirkstall Ltd, Sheffield, United Kingdom

COURSE DIRECTORS
ISABELLA DE ANGELIS - Istituto Superiore di Sanità - Viale Regina Elena, 299- 00162 Rome, Italy
ARTI AHLUWALIA - Università di Pisa, via Diotisalvi, 2 – 56100 Pisa, Italy

SCIENTIFIC SECRETARIAT
OLIMPIA VINCENTINI - Food Safety and Veterinary Public Health Dept.
Istituto Superiore di Sanità - Viale Regina Elena, 299- 00162 Rome
Tel: 06 4990 3631 Fax: 06 4990 3014
e-mail

TOMMASO SBRANA Interdepartmental Research Center "E. Piaggio"
University of Pisa, via Diotisalvi, 2 – 56100 Pisa, Italy
Tel: 050 2217050 Fax: 050 2217051
e-mail

GENERAL INFORMATION
Course Venue: Istituto Superiore di Sanità, Viale Regina Elena 299, Rome, Italy
Building 1, floor C, room number 74.
Number of participants: maximum 25 participants will be admitted

APPLICATION
Application available here, or can be downloaded here.

It should be duly filled, signed and sent, with a current CV, by e-mail or fax to: 050 2217051.

Applicants who have been accepted will receive a confirmation of admittance by e-mail.

Course fee: 125 euro (teaching materials and refreshments are included)
Travel and accommodation expenses are not included.

Payable to :
Bank name: Poste Italiane
Bank address: Pisa Centro, P.zza Vittorio Emanuele, Pisa, Italy
Bank account owner: Istituto Tecnologia E Vita
Bank account number: 7871350
IBAN: IT 28 I 07601 14000 000007871350
BIC-SWIFT: BPPIITRRXXX
The Istituto Tecnologia e Vita is a non-profit organization affiliated with the Interdepartmental Research Center "E. Piaggio" aimed at promoting and managing research activities. For information and registration please contact us here.

IMPORTANT DATES
5 September, 2012 - Deadline for application submission
7 September, 2012 - Confirmation of admittance
10 September, 2012 - Deadline for Registration fee payment