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ESTIV-CAAT-IVTIP Pre-congress Workshop

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Industrial and Regulatory Implementation of Non-Animal Integrated Testing Strategies Progress in skin sensitization and lessons learnt from other areas

10h00 – 12h30, 10 June 2014
Egmond aan Zee, The Netherlands

The pre-congress workshop will address the industrial and regulatory implementation of integrated testing strategies based on in silico, in chemico and in vitro test methods for the assessment of skin sensitization hazards and potential. For this purpose, lessons learnt from other areas will be presented, the definition and regulatory implementation of ITS will be given and examples of advanced strategies available on skin sensitization will be presented by speakers from different horizons (industry, academia, governmental bodies and NGOs). The session will end with round-table discussions to allow for exchanges and constructive discussions between the participants and the invited speakers.

Agenda

10.00-10.20
Constructing and evaluating  Integrated Testing Strategies (ITS) for Safety Assessment - Thomas Hartung, CAAT, US

10.20-10.40
Lessons learn from the regulatory implementation of ITS for eye irritation – Rodger Curren, IIVS, US (TBC)

10.40-11.00
Implementation of an Integrating Testing Strategy for Reproductive Toxicity from an industrial perspective, Dinant Kroese (TNO)/Bart van de Burg (BDS) – The Netherlands

11.00-11.20
OECD Integrated Approaches to Testing and Assessment for skin sensitization – João Barroso, EURL-ECVAM, IHCP, EC DG-JRC, Italy

11.20-11.40
Use of non-testing, in vitro and weight-of-evidence approaches in an IATA for Skin Sensitization – Emiel Rorije, RIVM, The Netherlands (TBC)

11.40-12.00
Bayesian ITS to assess skin sensitization potency - Joanna Jaworska, P&G, Belgium

12.00-12.30
Round table discussions

For more information see the ESTIV2014 webpage.

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