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Job Opening: Post-Doctoral Researcher (Human Toxome Project)

The Johns Hopkins Center for Alternatives to Animal Testing is involved in several scientific projects implementing the vision of Toxicity Testing in the 21st Century as formulated by the National Research Council report in 2007. The center is leading the NIEHS -funded Human Toxome Project, which is collaborative effort between CAAT, Georgetown University, Hamner Institute, Agilent and the US Environmental Protection Agency (EPA) to map pathways of toxicity. We are seeking a post-doctoral researcher to analyze and integrate multiple different data streams including, high-throughput screening data from the EPA ToxCast project.

Experience:
The candidate will develop/use computational tools to identify and evaluate putative predictors of toxic effects due to endocrine disruption. Required skills include empirical analysis of using HTS, metabolomics and proteomics data using machine learning methods, and pathway analysis using in-house and publicly available tools. Demonstrated experience with computer programming using open-source tools (R and/or Python) is a must.

Posted Qualifications:
PhD in computational biology/toxicology, bioinformatics, physics, computer science, mathematics or related field. Have some knowledge of pathway analysis approaches and experience in applying machine learning techniques to noisy data sets. Highly motivated and a self-starter, with the ability to work efficiently with minimal supervision. Additional education may substitute for required experience and additional related experience may substitute for required education, to the extent permitted by the JHU equivalency formula.

Location:
The position is located in Research Triangle Park, North Carolina at the National Center for Computational Toxicology of the US Environmental Protection Agency EPA and partly at the Johns Hopkins Center for Alternatives to Animal Testing, Baltimore MD.

Contact:
Andre Kleensang
Dr. rer. hum. biol.
Research Associate
akleensa@jhsph.edu
Johns Hopkins Center for Alternatives to Animal Testing (CAAT)
Johns Hopkins University
Bloomberg School of Public Health
615 N. Wolfe St., W7032
Baltimore, MD, 21205
phone: +1-410-614-4971
fax: +1-410- 614-2871

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Building a Better Epithelium: New Frontiers in 3D Conference
April 25, 2019
Cambridge, MA

CellTox 2019
May 7, 2019
Milano, Italy

Biosystems Engineering: Bioreactors and Cell Factories
May 12-17, 2019
Braunweld, Switzerland

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May 23-24, 2019
Neuchatel, Switzerland

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June 3-4, 2019
Beltsville, Maryland

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June 8-12, 2019
Tampa, Florida

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June 17, 2019
Berlin, Germany

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PBPK Modeling and Quantitative In Vitro-In Vivo Extrapolation
October 3-4, 2019
Wageningen, Netherlands

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October 17-18, 2019
Milan, Italy

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November 14-15, 2019
Geneva, Switzerland

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5th International Conference on Alternatives for Developmental Neurotoxicity (DNT) Testing
February 3-5, 2020
Konstanz, Germany

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