Skip Navigation

Organ-on-a-Chip Mimics Deadly Lung Condition

Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University have shown that their “lung-on-a-chip” technology can mimic a life-threatening lung condition. They also report that scientists can uncover new aspects of the disease using the lung chip that would not be found with animal experiments.

The study, published in today’s Science Translational Medicine, is the first definitive demonstration that the institute’s organ-mimicking chips, which include a gut, a heart, and a kidney (see “Building an Organ on a Chip”), can be used to model a disease and even test candidate drugs.

The lung-on-a-chip device is a clear, flexible thumb-sized block of polymer perforated by two tiny channels separated by a thin membrane. Air flows through one channel, which is lined with human lung cells; a nutrient-rich liquid that acts as a blood substitute flows through the other, which is lined with blood-vessel cells. A vacuum applied to chip moves the channels to re-create the way human lung tissues physically expand and contract when breathing.

Full article at MIT Technology Review

New ALTEX: 3/2015

Support ALTWEB, Make a Gift
Online Humane Science Course


ASCCT 4th Annual Meeting
October 1-2, 2015
Durham, NC
Turkheltox 2015
October 21-24, 2015
Cesme-Izmir, Turkey
November 1-5, 2015
Phoenix, AZ
Social Housing of Laboratory Animals
March 17-18, 2016
UC Davis, California
Pan-American Conference
April 12-14, 2016
Charles Commons, Johns Hopkins University
Baltimore, MD

More Meetings...