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Free eSeminar: Toxicogenomics in Environmental Science

Tuesday, September 22, 2015 11:00 am EDT

Program: Omics eSeminar Series

Panelist(s) Info: Natalia Garcia-Reyero, Associate Research Professor at Mississippi State University
Duration: 1 hour

Understanding potential hazards of chemicals released into the environment is challenging not only due to the large and growing number of chemicals and materials needing to be screened, but also the diverse environments, bioavailability, exposure conditions, and species differences that dramatically affect risks posed by chemicals. Examining effects on critical pathways resulting in adverse outcomes of interest such as reduced reproduction provides broader measure of potential hazards of a chemical. However, many of the biological pathways and key events that influence outcomes associated with chemical exposure are presently unknown or poorly defined. Gene expression approaches provide low throughput, high content transcriptome-wide data useful for assessment of chemical impacts. We will show how gene expression data can be used to elucidate potential adverse outcomes and explore its use for environmental monitoring.

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