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Too Many Mice are Sacrificed for Seriously Flawed Studies (Vox)

Excerpt from Vox:

In a new study published Tuesday in the journal Scientific Reportsresearchers found that breast cancer tumor cells from the same cell bank responded differently to the same chemical treatments. The cells were supposed to be clones — they had been vetted for quality before the experiment, and they came from one of the world’s best cell banks. They should have had the exact same responses to the chemicals.

Yet "there were dramatic [genetic] differences from one vial of these cells to another," said study leader Thomas Hartung, a professor in environmental health sciences and molecular microbiology and immunology at Johns Hopkins. He and his co-authors decided to investigate why, and discovered that the cells had undergone genetic drift.

Full Article (Vox)

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FRAME Training School in Experimental Design and Statistical Analysis
May 31-June 2, 2017
Saskatoon, Canada

Advances in Cell and Tissue Culture 2017
May 22-24, 2017
Manchester, UK

CAAT Academy
In Vitro Skin and Eye Models Hands-on Training
June 1-2 2017
Brussels, Belgium

CAAT Academy
Tools for Read-Across
June 15-16, 2017
Helsinki, Finland

ecopa SSCT Workshop 2017
June 14-16, 2017
Helsinki, Finland
Thomas Hartung will deliver a keynote address

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Updates on Hepatotoxicity AOP Landscape and on the ADME Field - Season 2
June 22-23, 2017
Rennes, France

9th Euro-Global Summit on Toxicology and Applied Pharmacology
June 22-24, 2017
Paris, France
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6th Annual Meeting of the American Society for Cellular and Computational Toxicology (ASCCT)
September 21-22
College Park, MD

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August 20-24, 2017
Seattle, Washington

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Hands-on Training in Quantitative Human Cell and Effect-based In Vitro Bioanalysis for Assessing Endocrine-disrupting Compounds (EDCs)
September 7-8. 2017
Amsterdam
 

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