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IIVS Awarded Grant to Develop Non-Animal Test for Respiratory Sensitization

The Institute for In Vitro Sciences, Inc. (IIVS) has received a grant from the Research Institute for Fragrance Materials (RIFM) to develop non-animal test methods for the evaluation of fragrance materials for potential respiratory irritation and sensitization. 

The grant was secured in collaboration with Liverpool John Moores University and the Physicians Committee for Responsible Medicine. The proposal, "The use of a novel non-animal platform to characterize respiratory effects of fragrance materials" combines computational approaches as well as in chemico techniques, and includes a testing plan in harmony with concepts for the OECD Adverse Outcome Pathway program. 

"The ability to evaluate the effect of fragrance materials on the respiratory system is significant for many industries. This project is expected to deliver far-reaching benefits to the scientific community for evaluating respiratory irritation and sensitization," said Dr. Holger Behrsing, Principal Scientist at IIVS and Primary Investigator on the project. "We are pleased that RIFM has chosen to promote the use of a non-animal approach for this investigation."

"The generation and distribution of high quality scientific data on the safety assessment of fragrances is central to our mission," said Dr. James Romine, President at RIFM. "RIFM is committed to the development of these data utilizing state-of-the-art technologies which don't require the use of animals."

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