ALTEX :: Alternatives to Animal Experiments

1994, SUPPLEMENT

CONTENTS :: MAIN ARTICLES

Animal Tests in Pharmacopoiea Monographs--Current State and Possibilities for Improvements
Ute Hechler and Klaus Cussler

Abnormal Toxicity--A Relevant Safety Test under GLP- and GMP-Conditions in the Production of Vaccines
Karin Duchow and Beate Kraemer

Recommendations of the ECVAM Workshop on "Alternatives to Animal Testing in the Quality Control of Immunobiologicals--State of the Art and Future Prospects"
Coenraad F.M. Hendriksen

The Importance of Endotoxin Producing Bacterias for Practical Purposes
Dietrich Schimmel

Investigations of the Endotoxin Content of Veterinary Vaccines
Klaus Cussler, Hannelore Godau and Heike Gyra

Replacement of the Toxin Neutralization Test in Mice by In Vitro Serological Assay Systems for Potency Testing of Tetanus Toxoid Vaccines for Veterinary Use: Results of a European Collaborative Study
Coenraad F.M. Hendriksen

Newer Knowledge Concerning a Protective Antigen of Erysipelothrix Rhusiopathiae
Reinhard Weiss, Marin H. Groschup and Claudia Nakov

Potency Testing of Erysipelas Vaccines in Mice--ELISA Versus Challenge
Rolf Beckmann and Klaus Cubler

Investigation about Development of Alternative Efficacy Verifications of Swine Erysipelas Vaccines
Heike Gyra, Renate Volmer and Dorothea Hausleithner

Diagnosis and Control of Progressive Atrophic Rhinitis (PAR) in Pigs
Peter Schoess

Detection of Pasteurella Multocida Toxin--A Comparison of In Vitro and In Vivo Methods
Dietrich Schimmel, Wilfried Erler, Ingrid Hänel and Wolfgang Mueller

Detection of Antibodies against Pasteurella Muldocida Toxin with a Cell Culture Method and an Enzyme Immunoassay
Volker Oeppling, Manuela Kusch, Petra Ruebmann and Klaus Cussler