ALTEX :: Alternatives to Animal Experiments

2004, Supplement Linz 03

CONTENTS :: MAIN ARTICLES

Induction, Expression and Maintenance of Cytochrome P450 Isoforms in Long-Term Cultures of Primary Human Hepatocytes
Jing Yuan, Liegang Liu, Masashi Shimada, Aiguo Wang, Maren Ruhnke, Peter Heeckt, Andrea R. Muller, Natascha C. Nussler, Peter Neuhaus and Andreas Nussler

Development of an In Vitro Model for Vascular Injury with Human Endothelial Cells
Claudia Schleger, Stefan J. Platz and Ulrich Deschl

Endocrine Toxicology -- Contributions of In Vitro Methods to the 3R Concept
Alexius Freyberger and Gabriele Scholz

Toxicoproteomics: First Experiences in a BMBF-Study
Michaela Kröger, Jürgen Hellmann, Luca Toldo, Matthias Glückmann, Bettina von Eiff, Kerstin Fella and Peter-Jürgen Kramer

Neurotoxicity of Active Compounds -- Establishment of hESC-lines and Proteomics Technologies for Human Embryo- and Neurotoxicity Screening and Biomarker Identification
Martina Klemm and André Schrattenholz

Ischemia Reperfusion Injury in the Isolated Hemoperfused Bovine Uterus -- A Model for the Investigation of Anti-Inflammatory Substances?
Michael Braun and Manfred Kietzmann

Validation of Cell Culture Models for the Intestine and the Blood-Brain Barrier and Comparison of Drug Permeation
Udo Bock, Thomas Flötotto and Eleonore Haltner

Quality Assurance of C. perfringens Epsilon Toxoid Vaccines -- ELISA Versus Mouse Neutralisation Test
Ute Rosskopf-Streicher, Peter Volkers, Kerstin Noeske and Esther Werner

Chips Instead of Mice: Cells on Bioelectronic Sensor-Chips as an Alternative to Animal Experiments
Angela M. Otto, Martin Brischwein, Elena Motrescu, Eléonore Cabala, Helmut Grothe, Christoph Stepper und Bernhard Wolf

1D-and 3D- Computer Simulation for Planning and Interpretation of Pharmacokinetic Studies in the Inner Ear After Round Window Drug Delivery
Stefan Plontke, Norbert Siedow, Hartmut Hahn, Raimund Wegener, Hans-Peter Zenner and Alec N. Salt