ATLA :: Alternatives to Laboratory Animals

Volume 25, Number 3
May/June 1997

CONTENTS

EDITORIAL

Non-animal alternatives and reduction in laboratory animal use

NEWS AND VIEWS

ARTICLES

ECVAM Workshop Report

The development and validation of expert systems for predicting toxicity.
J.C. Dearden, M.D. Barratt, R. Benigni, D.W. Bristol, R.D. Combes, M.T.D. Cronin, P.N. Judson, M.P. Payne, A.M. Richard, M. Tichy, A.P. Worth & J.J. Yourick

The Fourteenth Congress on In Vitro Toxicology of the Scandinavian Society for Cell Toxicology

Detoxification strategies of two types of spiders revealed by cypermethrin application.
S. Achim Nielson, J. Clausen & S. Toft

An ultrastructural evaluation of the SKIN²™ ZK1200 system as an in vitro model of the human oral mucosa.
D. Arenholt-Bindslev, L. Andersen Torpet & K. Josephsen

Cadmium-induced inhibition of ADH-stimulated ion transport in cultured kidney-derived epithelial cells (A6).
H.F. Bjerregaard & B. Faurskov

An in vitro system for evaluation of oxidative stress and the effects of antioxidants.
B. Brogaard & J. Clausen

5'-Nucleotidase activity and galactolipid accumulation in triethyllead-exposed glial cell cultures.
I.K. Grundt, M. Rise & H. Nyland

Mechanisms of tamoxifen's retinal toxicity, studied in pig pigment epithelial cell cultures.
H. Mäenpää, T. Toimela, P. Saransaari, L. Salminen & H. Tähti

Neurotoxicity of seven MEIC chemicals evaluated in organotypic cultures of chick embryonic dorsal root ganglia.
V. Mandys, K. Jirsová & J. Vrana

Genotoxicity screening of leachates from solid industrial wastes evaluated with the Allium test.
P.G. Odeigah, J. Ijimakinawa, B. Lawal & R. Oyeniyi

Cytotoxicity of metal cations used in dental cast alloys.
G. Schmalz, D. Arenholt-Bindslev, S. Pfüller & H. Schweikl

Cytotoxicity of MEIC chemicals to rainbow trout R1 cell line and multivariate comparison with ecotoxicity tests.
H. Segner & G. Schüürmann

In vitro tets in pharmacotoxicology: can we fill the gap between scientific advances and industrial needs?.
R. Shrivastava

Cytotoxic and genotoxic effects of sodium fluoride on mammalian cells at neutral or acid pH: a summary of published work.
D. Slameñová, A. Gábelová, K. Ruppová & L. Wsólová

An animal protection sponsor's view of MEIC.
E. Thurston

Automated in vitro dermal absorption (AIVDA): a new in vitro method for investigating transdermal flux.
R.P. Moody

The prediction of skin permeability by using physicochemical data.
L.A. Kirchner, R.P. Moody, E. Doyle, R. Bose, J. Jeffery & I. Chu

COMMENT

A critical analysis of the testing of the testing of potentially carcinogenic food contaminants
C.L. Broadhead & R.D. Combes

AROUND THE WORLD

Swiss academy of medical sciences and Swiss academy of sciences: ethical principles and guidelines for scientific experiments on animals

CONFERENCE REPORTS

CONFERENCE DIARY

BOOK REVIEWS

Environmental enrichment in captive primates: a survey and review / Cytochromes P450: structure, function and mechanism / In vitro methods in pharmaceutical research

SELECTED TITLES