ATLA :: Alternatives to Laboratory Animals

Volume 27, Number 5
November/December 1999

CONTENTS

EDITORIAL

Precautions and claims for "safety" based on inadequate risk assessment are hazardous and expose all concerned to risk

NEWS AND VIEWS

FRAME ANNUAL LECTURE
Professor W.M.S. Russell

ARTICLES

Gastrulating Rat Embryo in a Serum-free Culture Model: Changes of Development Caused by Teratogen 5-Azacytidine.
F. Bulic-Jakus, M. Vlahovic, G. Juric-Lekic, V. Crnek-Kunstelj & D. Serman

Description of a dynamic in vitro model of the dog gastrointestinal tract and an evaluation of various transit times for protein and calcium.
M.J.E. Smeets-Peeters, M. Minekus, R. Havenaar, G. Schaafsma & M.W.A. Verstegen

Effects of chromatin function inhibitors on yeast whole cells and spheroplasts.
E. Tiligada, E. Stavrinidis, C. Manolis & A. Delitheos

Determination of the starting dose for acute oral toxicity (LD50) testing in the Up and Down Procedure (UDP) from cytotoxicity data.
H. Spielmann, E. Genschow, M. Liebsch & W. Halle

COMMENT

Laboratory animal consciousness and feelings: adopting the precautionary principle.
R.H. Bradshaw

CONFERENCE DIARY

BOOK REVIEWS

Occupational health and safety in the care and use of research animals / Attitudes to animals: views in animal welfare.

SELECTED TITLES