ATLA :: Alternatives to Laboratory Animals

Volume 28, Number 1
January/February 2000

CONTENTS

THE THREE RS DECLARATION OF BOLOGNA

Reduction, refinement and replacement alternatives and laboratory animal procedures

NEWS AND VIEWS

ARTICLES

Development of a decision support system for the introduction of alternative methods into local irritancy/corrosivity testing strategies. Development of a relational database.
I. Gerner, G. Graetsche, J. Kahl & E. Schlede

Local irritation/corrosion testing strategies: development of a decision support system for the introduction of alternative methods.
S. Zinke, I. Gerner, G. Graetschel & E. Schlede

Testing wound-healing activity in T15 fibroblast cultures: a morphometric analysis.
S. Korkmaz, H. Zeytinoglu, M. Zeytinoglu, S. Aydin, Y Oztuk & H. Can Baser

Development of a gill perfusion apparatus for studying the interaction of fish pathogens with gill tissue.
H. Spielmann, E. Genschow, M. Liebsch & W. Halle

Evaluation of various immunisation procedures in laying hens to induce high amounts of specific egg yolk antibodies.
M.H. Erhard, K Mahn, P. Schmidt, S. Oltmer, R. Preisinger, P. Zinsmeister & M. Stangassinger

Endocrine disruptors: a critical review of in vitro and in vivo testing strategies for assessing their toxic hazard to humans.
R.D. Combes

ECVAM WORKSHOP REPORT

Biomarkers as predictive tools in toxicity testing.
D.J. Benford, A.B. Hartley, K. Bottrill, S. Oehlschlager, M. Balls, F. Branca, J. Jaques Castegnaro, J. Descotes, K Hemminiki, D. Lindsay & B. Schilter

COMMENT

Developments in the collection of statistical information on the number of animals used in experiments and other scientific purposes in the European Union.
U.G. Sauer & R. Kolar

BOOK REVIEWS

Ethics, animals and science.

CONFERENCE DIARY

SELECTED TITLES