ATLA :: Alternatives to Laboratory Animals

Volume 28, Number 3
May/June 2000

CONTENTS

EDITORIAL

Testing biocides -- will common sense prevail?

ARTICLES

The ECVAM prevalidation study on the use of EpiDerm for skin corrosivity testing.
M. Liebsch, D. Traue, C. Barrabas, H. Spielmann, P. Uphill, S. Wilkins, J.P. McPherson, C. Wiemann, T. Kaufmann, M. Remmele & H-G. Holzhütter

Structure-permeability relationships for transcorneal penetration.
A.P. Worth & M.T.D. Cronin

In vitro cytotoxicity of four different buffers for use in peritoneal dialysis.
L.E. Järkelid, E. Svensson, R. Deppisch & A. Wieslander

Iron-induced lipid peroxidation in human skin-derived cell lines: protection by a red orange extract.
F. Morini, F. Dusatti, F.P. Bonina, A. Saija & M. Ferro

The Seventeenth Workshop of the Scandinavian Society for Cell Toxicology

Effects on detoxification enzymes in different life stages of honey bees (Apis mellifera L. Hymenoptera: Apidae) treated with a synthetic pyrethroid flumethrin).
S.A. Nielsen, C.J. Brødsgaard & H. Hansen

Activities of glutathione S-transferase and glutathione peroxidases related to diet quality in an aphid predator, the seven-spot ladybird, Coccinella septempunctata L. (Coleoptera: Coccinellidae).
S.A. Nielsen, M.S. Hauge, F.H. Nielsen & S. Toft

A new mechanism of mammalian cell resistance to the toxic effects of DNA-binding agents.
V. Levina, E. Varfolomeeva, E. Sukhareva, E. Shabalina, E. Drobehenko & M. Filatov

Gill epithelial cells as in vitro models in aquatic toxicology.
M. Sandbacka, I. Christianson & B. Isomaa

Toxicological investigation of soils with the soild-phase flash assay: Comparison with other ecotoxicological tests.
Lee Põllumaa, Anne Kahru, Adolf Eisenträger, Rain Reiman, Alla Maloveryan and Annely Rätsep

Cytotoxicity of cadmium, selenium, zinc and copper to mouse myeloma Sp2/0 cells as measured by the MTT assay.
I. Remez, L. Rabkin, H. Veksler & M. Baumane

Retinal Müller cell culture.
T. Toimela, H. Mäenpää & H. Tähti

Surface-adhering human leucocytes: an in vitro model for cytotoxicity testing of fluids.
H. Nygren, M. Braide, C. Eriksson & N. Yahyapour

Toxicity testing of polymer materials for dialysis equipment: reconsidering in vivo testing.
P. Kjellstrand, E. Lindqvist & C. Nilsson-Thorell

Host plant effects on activities of detoxification enzymes and insecticide tolerance in western flower thrips. Frankliniella occidentalis (Insecta).
S.E. Jensen & H.F. Brødsgaard

Toxicological evaluation of surface-water samples in sensitised cultured fish cells compared with the Microtoxµ method.
P.J. Dierickx, C. Van der Wielen & S. Lemair

COMMENT

Comments on the European Community strategy for endocrine disruptors.
B. Phillips

Application of the Three Rs principle in the compilation of "Technical Guidance Document in Support of Directive 98/8/EC Concerning the Placing of Biocidal Products on the Market. Part I. Guidance on Data Requirements for Active Substances and Biocidal Products."
U.G. Sauer, M. Liebsch & R. Kolar

AROUND THE WORLD

Spanish Activities on Alternatives

CONFERENCE DIARY

BOOK REVIEWS

Handbook of laboratory animal management and welfare / Neurotoxicology in vitro / General and Applied Toxicology