ATLA :: Alternatives to Laboratory Animals

Volume 30, Number 1
January / February 2002

CONTENTS

EDITORIAL
The EU White Paper: Strategy for a Future Chemicals Policy (an idea that must have seemed good at the time!)

PREFACE

NEWS AND VIEWS

ARTICLES

Alternatives to animal testing in the safety evaluation of products.
D.J. Knight & D. Breheny

A comparative study of the toxicity of mercury dichloride and methylmercury, assayed by the frog embryo teratogenesis assay-Aenopus (FETAX).
M. Prati, R. Gornati, P. Boracchi, E. Biganzoli, S. Fortaner, R. Pietra, E. Sabbioni & G. Bernardini

Use of a cell transformation assay with established cell fines, and a metabolic cooperation assay with V79 cells for the detection of tumour promoters: a review.
A. Sakai, Y. Iwase, Y. Nakamura, K. Sasaki, N. Tanaka & M. Umeda

Cystathionine pathway-dependent cytotoxicities of diethyl maleate and diamide in rat and human hepatoma-derived cell cultures.
P.J. Dierickx, J.O. De Beer & E.M. Scheers

Cytostatic properties of a novel compound derived from Penicillium pinophilum: an in vitro study.
A. Stammati, R. Nicoletti, S. De Stefano, F. Zampaglioni & F. Zucco

Detection of the embryotoxic potential of cyclophosphamide by using a combined system of metabolic competent cells and embryonic stem cells.
S. Bremer, C. Pellizzer, S. Coecke, M. Paparella & P. Catalani

Use of the SOS-chromotest spot assay as a screening system for detecting genotoxic compounds in crude plant extracts.
D.A. Baez, G.Z. Vallejo, P.C. S´nchez, M.B. Valle, R.R. Chilpa & M.J. Estrada

Comparative evaluation of five in vitro tests for assessing the eye irritation potential of hair-care products.
P.A. Jones, E. Budynsky, K.J. Cooper, D. Decker, H.A. Friffiths & J.H. Fentem

ECVAM's contributions to the implementation of the Three Rs in the production and quality control of biologicals.
M. Halder, C. Hendriksen, K. Cussler & M. Balls

ECVAM TASK FORCE REPORT

Follow-up to the ECVAM prevalidation study on in vitro tests for acute skin irritation
V. Zuang, M. Balls, P.A. Botham, A. Coquette, E. Corsini, R.D. Curren, G.R. Elliott, J.H. Fentem, J.R. Heylings, M. Liebsch, J. Medina, R. Roguet, J.J.M. van de Sandt, C. Wiemann & A.P. Worth

COMMENT

A critique of the Animal Procedures Committee report on biotechnology
E.S. Jenkins & R.D. Combes

CONFERENCE DIARY

SELECTED TITLES