ATLA::Alternatives to Laboratory Animals

Volume 30, Supplement 2

ECVAM's research and validation activities in the fields of topical toxicity and human studies

ATLA 30, Supplement 2, 115-118, 2002

Valérie Zuang

ECVAM, Institute for Health & Consumer Protection, European Commission Joint Research Centre, 21020 Ispra (VA), Italy

SUMMARY

This paper outlines the research, prevalidation and validation activities that ECVAM has undertaken in collaboration with its partners in the field of topical toxicity testing and human volunteer studies, from its creation until now (1994-2002).

Keywords: alternative methods, animal testing, cosmetics testing, eye irritation, human volunteer studies, phototoxicity, skin toxicity, validation