Adjuvants in Laboratory AnimalsEvaluation of immunostimulating properties and side effects of Freund's complete adjuvant and alternative adjuvants in immunization procedures Printed by: Ponsen & Looijen BV, Wageningen
Authored by: Dr. P.P.A. Marlies Leenaars
The studies presented in this thesis were perfommed at the Division Immunological and Infectious Diseases (I&I), TNO Prevention and Health (TNO-PG), Leiden, the Netherlands, and the Central Animal Laboratory, National Institute of Public Health and the Environment (RIVM), Bilthoven, the Netherlands. The research was financially supported by the RIVM-lnstitute's Centre for Alternatives to Animal Testing, Bilthoven, the Division I&I, TNO-PG, Leiden and the Department of Immunology, Erasmus University, Rotterdam. The printing of this thesis was financially supported by:
RlVM-lnstitute's Centre for Altematives to Animal Testing, Bilthoven
TNO-PG, Leiden
Erasmus University, Rotterdam Contents | List of abbreviations | | Chapter 1 | Introduction | | Chapter 2 | Antigens and antigen presentation
Immunology Methods Manual, 1997, pp. 989-1013 | | Chapter 3 | Evaluation of several adjuvantsas alternatives
to the use of Freund's adjuvant in rabbits
Vet. Immunol. Immunopathol., 1994, 40: 225-241 | | Chapter 4 | Comparison of several types of adjuvants for immune
potentiating properties and side effects in mice
Vet Immunol. Immunopathol., 1995, 48: 123-138 | | Chapter 5 | Assessment of side effects induced by injection of different
adjuvanVantigen combinations in rabbits and mice
submitted | | Chapter 6 | Immune responses and side effects of five different oil
based adjuvants in mice
Vet Immunol. Immunopathol., in press | | Chapter 7 | Model to test efficacy of immunization procedures by
early cytokine production in mice
Animal Altematives Welfare and Ethics, 1997, in press | | Chapter 8 | Increased adjuvant efficacy in stimulation of antibody
responses after macrophage elimination in viva
Immunology, 1997, 90: 337-343 | | Chapter 9 | A rapid and simple method to localize oil based
adjuvants in viva
J. Immunol Methods, in press | | Chapter 10 | General discussion References
Summary
Samenvatting
Curriculum vitae
List of publications
APPENDIX A, B |
| MeetingS | Workshop: Lessons Learned, Challenges, and Opportunities: The US Endocrine Disruptor Screening Program
April 23-24, 2013
Research Triangle Park, NC Developing Microphysiological Systems for Use as Regulatory Tools- Challenges and Opportunities
May 10, 2013
Silver Spring, MD Advances in In Vitro Cell and Tissue Culture
May 21-22, 2013
Liverpool, England Joint US Workshop: Scientific Roadmap for the Future of Animal-Free Systemic Toxicity Testing
May 30-31, 2013
College Park, MD International Congress of Toxicology
June 30-July 4, 2013
Seoul, Korea EUSAAT's 2013 Congress and Symposium
September 13-18th, 2013
Linz, Austria LATINFARMA 2013: 3Rs Alternatives in Pharmacology, Toxicology and Teaching Workshop
October 21-25, 2013
La Habana, Cuba In Vitro Medical Device Testing Symposium
December 10-11, 2013
Baltimore, MD More Meetings... |
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