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The following links were selected because they contain information and resources of interest to the U.S. and International Scientific Community. For a complete list of related Web sites linked to Altweb, check out the Johns Hopkins Center for Alternatives to Animal Testing (CAAT) related links page.

We're always looking for new Web sites, provided they support the concept of the "Three Rs." We define alternatives as methods that refine existing tests to lessen animal pain and distress, reduce the number of animals needed for a test, or replace animals with other methods. If you have a site to recommend, let us know!

We've also compiled a list of the many other 3Rs centers from around the globe.

See also: Search for Alternatives, Databases, and Statistics


3Rs and Alternatives Organizations

International 3Rs and Alternatives Organizations Site

Listing of 3Rs and Alternatives Organizations

3Rs—Definitions and Descriptions

Alternatives in Education

Animal Use Information/Statistics

Bioethics in Animal Research

Biomedical Research Organizations

Databases (see also Search for Alternatives)

Environmental Enrichment (see also Refinement)

Funding in the 3Rs

Government Agencies

Humane Science (see also 3Rs)

In Vitro Science

Institutional Animal Care & Use Committees (IACUCs)/Ethical Review Committees


Laboratory Animal Welfare

Legislation, Regulations, Guidelines

Non-mammalian Models (fish, reptiles and amphibians, C. elegans)

Pain & Distress (see also Refinement)

Reduction (experimental design, statistical analysis)

Refinement (housing, handling, husbandry)

Replacement (in vitro methods, computer simulations, manikins, and models)

Research Programs

Search for Alternatives (see also Databases)

Toxicology/Toxicity Testing

World Congress on Alternatives and Animal Use in the Life Sciences

Links for Teens and Kids

Animal Protection Sites

Cool Animal Sites

Cool Science Sites

Humane Treatment of Farm Animals

Use of Animals in Biomedical Research

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Online Humane Science Course


Building a Better Epithelium: New Frontiers in 3D Conference
April 25, 2019
Cambridge, MA

CellTox 2019
May 7, 2019
Milano, Italy

Biosystems Engineering: Bioreactors and Cell Factories
May 12-17, 2019
Braunweld, Switzerland

ALTERTOX Academy Training:
In Vitro Exposure Systems and Dosimetry Assessment Tools for Inhalation Toxicology
May 23-24, 2019
Neuchatel, Switzerland

6th Symposium on Social Housing of Laboratory Animals
June 3-4, 2019
Beltsville, Maryland

Society for In Vitro Biology Annual Meeting
June 8-12, 2019
Tampa, Florida

Upcoming: CAAT-Europe Information Day On Biology-inspired Microphysiological Systems (MPS) to Advance Medicines for Patients' Benefit
June 17, 2019
Berlin, Germany

ALTERTOX Academy Training:
PBPK Modeling and Quantitative In Vitro-In Vivo Extrapolation
October 3-4, 2019
Wageningen, Netherlands

ALTERTOX Academy Training:
Novel In Silico Models for Assessment of Cosmetics
October 17-18, 2019
Milan, Italy

ALTERTOX Academy Training:
In Vitro Lung Models
November 14-15, 2019
Geneva, Switzerland

Save the Date!
5th International Conference on Alternatives for Developmental Neurotoxicity (DNT) Testing
February 3-5, 2020
Konstanz, Germany

Full Listing of CAAT Programs
and Activities