Proceedings of the Production of Monoclonal Antibodies Workshop

August 29, 1999 | Bologna, Italy

This document has been adapted with permission from a publication created by the Alternatives Research & Development Foundation (ARDF)

Table of Contents

Acknowledgements

Introduction

Production of Monoclonal Antibodies by the Ascites Method: Animal Welfare Implications
Coenraad Hendriksen

Consideration of the Advantages and Disadvantages of In Vitro and Ascites Production of MAbS
John McArdle

Small-Scale Monoclonal Antibody Production In Vitro: Methods and Resources
Lynn Jackson, Laura Trudel, Neil Lipman

Commercial Production of Monoclonal Antibodies
Simon Saxby

A Comprehensive Cost Comparison of In Vitro and Ascites Approaches to MAb Production
Norman Peterson

Comments on Scientific Justifications Offered to Support the Use of th Ascites Method to Produce Monoclonal Antibodies
Uwe Marx

IACUC Guidance Document and Checklist for Evaluation of Monoclonal Antibody Production -- In Vitro vs Ascites
Louis DeTolla, Joanne Smith

Comparison of CAAT, ECVAM, and ILAR Reports on Monoclonal Antibody Production
Peter Theran

Conclusions and Recommendations

Appendix A: Biographical Sketches of Workshop Participants

Appendix B: Essential References and Websites