Skip Navigation

Proceedings for "Alternatives in Monoclonal Antibody Production"

September 24-25, 1997 | Baltimore, MD

A workshop of The Johns Hopkins Center for Alternatives to Animal Testing and The Office for Protection from Research Risks, National Institutes of Health

Presentation of the Issue
Nelson Garnett, DVM, Director, Division of Animal Welfare, Office for Protection from Research Risks, NIH
John McArdle, PhD, Director, Alternatives Research & Development Foundation

Scientific Presentations: State-Of-The-Science Methods For Mab Production--Advantages and Disadvantages

"Overview: The Science and Uses of Monoclonal Antibodies"
Mark Soloski, PhD, Associate Professor of Rheumatology, Johns Hopkins University School of Medicine

"Hollow Fiber Bioreactors: An Alternative to the Use of Mice for MAB Production"
Neil S. Lipman, VMD, Director of the Research Animal Resource Center and Associate Professor of Pathology, Cornell University Medical College and the Memorial Sloan-Kettering Cancer Center

"Comparison of Hollow Fiber Bioreactors and Modular Minifermentors for the Production of MABs In Vitro"
Howard T. Petrie, PhD, Assistant Member, Immunology Program Director, Monoclonal Antibody Core Facility, Memorial Sloan-Kettering Cancer Center

"The Use of Gas-Permeable Bags for MAB Production"
Jerry R. Heidel, DVM, Associate Professor, College of Veterinary Medicine, Oregon State University

"Practical Applications and Comparison of Ascites and In Vitro Methods for MAB Production"
Norman C. Peterson, DVM, MS, Research Associate in Pathology and Laboratory Medicine, University of Pennsylvania Medical School

"Ascites Alternatives: A Comparison of Lab-Scale Production of Monoclonal Antibodies in the Unisyn Cell-Pharm System 100 and the miniPERM Bioreactor"
Frank W. Falkenberg, Professor, Ruhr-Universitat Bochum, Germany

Special Lecture: "Animal Welfare Concerns about Monoclonal Antibody Production"
Andrew N. Rowan, DPhil, Senior Vice President, Humane Society of the United States

Panel Presentations and Discussion: IACUCS--Responsibilities and Needs in Advising Investigators

Marcia Etheridge, DVM, Assistant Professor of Comparative Medicine, JHU School of Medicine

Lou DeTolla, VMD, PhD, Director of Comparative Medicine Programs and Chief of Veterinary Resources, University of Maryland School of Medicine

DeWayne H. Walker, DVM, Manager of Laboratory Animal Research Services, 3M Corporation

Core Laboratories: What is Their Cost-Effectiveness and What are Their Needs?

Margaret B. Penno, PhD, Associate Professor of Medicine, JHU School of Medicine

Panel Presentation and Discussion: Regulatory Issues in the United States


Louis R. Sibal, PhD, Director, Office of Laboratory Animal Research, NIH

Jerry D. DePoyster, DVM, Veterinary Medical Officer, U.S. Department of Agriculture

William S. Stokes, DVM, Associate Director, Animals and Alternatives, National Institute of Environmental Health Sciences and Director, Interagency Coordinating Committee on the Validation of Alternative Methods

The European Perspective

Coenraad Hendriksen, DVM, PhD, National Institute of Public Health and Environmental Protection, The Netherlands


New ALTEX: 2/2018

ALTEX cover 51

Support ALTWEB, Make a Gift
Online Humane Science Course


Building a Better Epithelium: New Frontiers in 3D Conference
April 25, 2019
Cambridge, MA

CellTox 2019
May 7, 2019
Milano, Italy

Biosystems Engineering: Bioreactors and Cell Factories
May 12-17, 2019
Braunweld, Switzerland

ALTERTOX Academy Training:
In Vitro Exposure Systems and Dosimetry Assessment Tools for Inhalation Toxicology
May 23-24, 2019
Neuchatel, Switzerland

6th Symposium on Social Housing of Laboratory Animals
June 3-4, 2019
Beltsville, Maryland

Society for In Vitro Biology Annual Meeting
June 8-12, 2019
Tampa, Florida

Upcoming: CAAT-Europe Information Day On Biology-inspired Microphysiological Systems (MPS) to Advance Medicines for Patients' Benefit
June 17, 2019
Berlin, Germany

ALTERTOX Academy Training:
PBPK Modeling and Quantitative In Vitro-In Vivo Extrapolation
October 3-4, 2019
Wageningen, Netherlands

ALTERTOX Academy Training:
Novel In Silico Models for Assessment of Cosmetics
October 17-18, 2019
Milan, Italy

ALTERTOX Academy Training:
In Vitro Lung Models
November 14-15, 2019
Geneva, Switzerland

Save the Date!
5th International Conference on Alternatives for Developmental Neurotoxicity (DNT) Testing
February 3-5, 2020
Konstanz, Germany

Full Listing of CAAT Programs
and Activities